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Building a city is awesome and anyone that has ever played SimCity will attest to it. However, the complex nature of it suits computer games better than board games which results in city building board and card games being usually based on something other than balancing RCI. Sure, there is Alhambra with its many expansions but that is not really a city building game either. It's laying tiles to each other so that they connect with walls. More like a logical puzzle, I'd say.
The City is not about balancing RCI either but it's more city building than any other board game I've played. As with most of the card games, the luck plays a large part here. You are dealt some cards and for the couple first rounds, as you're building your first buildings, you try to set a specialization of your future city. Each building has some attributes and most of them react to other buildings in your city, so of course, you are trying to create such building combinations that give you some very nice bonuses.